The Peter Attia Drive
Peter Attia, MD
Immerse yourself in the world of longevity and peak performance with "The Peter Attia Drive" podcast. Hosted by Dr. Peter Attia, this thought-provoking series dives deep into the science of longevity, exploring cutting-edge research and practical insights to enhance lifespan and healthspan. Dr. Attia's engaging approach brings clarity to complex medical topics, making it accessible to both medical professionals and everyday health enthusiasts. Each episode is meticulously crafted, featuring conversations with leading experts in fields ranging from nutrition and exercise to sleep and mental health, delivering actionable strategies that can transform your health and well-being. Whether you're a fitness aficionado seeking the latest trends in wellness or someone curious about the scientific underpinnings of a healthy life, "The Peter Attia Drive" offers a wealth of knowledge. Dr. Attia's commitment to evidence-based medicine and his passion for improving quality of life shines through in every discussion, ensuring listeners walk away with valuable tips and a deeper understanding of how to live a healthier, more vibrant life. Tune in to "The Peter Attia Drive" and start your journey towards a longer, fuller life today.
Episodes
Zone 2 training: impact on longevity and mitochondrial function, how to dose frequency and duration, and more | Iñigo San-Millán, Ph.D. (#201 rebroadcast)
In this rebroadcast of a popular episode from March 2022, host Dr. Peter Attia revisits a comprehensive discussion with Dr. Iñigo San-Millán on the nuances of Zone 2 training. They explore how this exercise intensity, known for optimizing fat oxidation and enhancing mitochondrial function, plays a crucial role in athletic performance and general health. The conversation includes practical insights on measuring Zone 2, integrating it into training regimes, and its profound impacts on metabolic health. This detailed dialogue not only illuminates the physiological mechanisms behind Zone 2 training but also provides actionable advice for individuals aiming to incorporate these strategies into their fitness routines.
#308 - AMA #61: Sun exposure, sunscreen, and skin health: relationship between sun exposure and skin cancer, vitamin D production, and photoaging, how to choose a sunscreen, and more
In this informative episode, Dr. Peter Attia and co-host Nick Stenson tackle critical topics surrounding sun exposure, including its impact on skin cancer, vitamin D synthesis, and the aging of skin. They start by defining ultraviolet (UV) radiation and its roles, emphasizing the balance necessary between beneficial and harmful effects of sun exposure. Detailed discussions cover the types of skin cancers, the mechanisms of vitamin D production, and the distinction between UVA and UVB rays. The episode also provides a comprehensive guide on choosing the right sunscreen, distinguishing between organic and mineral sunscreens, and debunking common myths surrounding SPF and sunscreen efficacy.
#307 - Exercise for aging people: where to begin, and how to minimize risk while maximizing potential | Peter Attia, M.D.
Dr. Peter Attia addresses the common concerns of older adults regarding starting exercise routines. He emphasizes the importance of exercise for longevity and health, especially for those above 50. The episode discusses four main pillars of exercise—stability, strength, aerobic efficiency, and peak aerobic output—and how they cater to the needs of the aging population. Dr. Attia blends scientific insights with practical advice, making it accessible for listeners to understand how to begin exercising safely and effectively. He shares various strategies to minimize injury and maximize potential, providing a comprehensive guide tailored to the capabilities and limitations of older adults.
#306 - AMA #60: preventing cognitive decline, nutrition myths, lowering blood glucose, apoB, and blood pressure, and more
In AMA #60, Peter Attia, alongside co-host Nick Stenson, explores a variety of health-related topics in a quick Q&A format. They tackle pressing issues such as cognitive decline, the relationship between cardiovascular disease and Alzheimer’s, metabolic health, and more. The episode provides insights into maintaining cognitive function through lifestyle choices, including exercise, diet, and sleep. The discussion also debunks common nutrition myths and emphasizes the importance of metabolic health, particularly focusing on how blood glucose, insulin, and ApoB levels impact overall health. This episode is a treasure trove of practical advice for anyone looking to enhance their healthspan and understand the science behind common health recommendations.
#305 - Heart rate variability: how to measure, interpret, and utilize HRV for training and health optimization | Joel Jamieson
In a comprehensive discussion with host Peter Attia, Joel Jamieson, the CEO and founder of Morpheus Labs, sheds light on heart rate variability (HRV), a critical metric for monitoring the autonomic nervous system's health. Jamieson explains the nuances of HRV, including its calculation, implications, and the tools available for accurate measurement. The episode offers a deep dive into how HRV reflects the balance between sympathetic and parasympathetic nervous activities and its significance in predicting health outcomes and optimizing training regimens. The conversation also covers the influence of lifestyle choices on HRV and its role alongside other health metrics.
#304 - NEW: Introducing quarterly podcast summaries - Peter shares his biggest takeaways on muscle protein synthesis, VO2 max, toe strength, gut health, and more
In this episode, Peter Attia revisits the highlights from the last quarter's podcasts. He shares insights gained on topics ranging from muscle protein synthesis and VO2 max to toe strength, gut health, and more. Through interviews with experts like Luke Van Loon and others, Peter distills complex scientific discussions into key lessons and personal reflections, even discussing how these insights have influenced his own health practices and patient advice. The episode serves as both a summary and a deeper dive into actionable health strategies, emphasizing the practical applications of the discussed research and theories.
#303 - A breakthrough in Alzheimer's disease: the promising potential of klotho for brain health, cognitive decline, and as a therapeutic tool for Alzheimer's disease | Dena Dubal, M.D., Ph.D.
In this engaging episode of "The Peter Attia Drive," Dr. Peter Attia hosts Dr. Dena Dubal to discuss the remarkable potential of klotho in Alzheimer's disease prevention and treatment. Klotho, a protein associated with longevity, shows promise in enhancing brain resilience, cognitive functions, and overall brain health. Dr. Dubal, a leading expert in neurology and neuroscience, shares insights from her extensive research, highlighting klotho's effects across various species and its significant implications for neurodegenerative diseases like Alzheimer's. The discussion explores the biological mechanisms of klotho, its impact on cognitive functions, and potential pathways for clinical applications, offering hope for future therapies.
#302 - Confronting a metabolic epidemic: understanding liver health and how to prevent, diagnose, and manage MAFLD and liver disease | Julia Wattacheril, M.D., M.P.H.
In this insightful episode of "The Peter Attia Drive," Dr. Peter Attia hosts Dr. Julia Wattacheril, a specialist in non-alcoholic fatty liver disease (NAFLD) and related conditions. They delve into liver physiology, the history of liver diseases, and liver transplantation, addressing both alcohol-related and non-alcoholic liver injuries. The conversation highlights the liver's critical functions, its susceptibility to injury, and the stages of liver disease, emphasizing the importance of early diagnosis and intervention. Dr. Wattacheril also discusses the evolution of liver disease treatment and the challenges faced in mimicking liver functions through external devices.
#301 - AMA #59: Inflammation: its impact on aging and disease risk, and how to identify, prevent, and reduce it
In this insightful episode, Dr. Peter Attia alongside co-host Nick Stenson, unpacks the complexities of inflammation, distinguishing between acute and chronic types and exploring their links to aging and disease. They dissect how chronic inflammation is tied to various health issues like obesity and metabolic syndrome, and how it can significantly increase disease risk. The discussion is rich with actionable insights on identifying inflammation through biomarkers like CRP and serum albumin, and the use of diets, lifestyle changes, and medical interventions to manage it. This episode is pivotal for anyone looking to understand and mitigate the impacts of inflammation on their health.
#300 - Special episode: Peter on exercise, fasting, nutrition, stem cells, geroprotective drugs, and more - promising interventions or just noise?
In this milestone 300th episode, host Peter Attia explores a range of health-related topics including geroprotective drugs, exercise regimes, nutritional plans, and more. Peter categorizes these interventions into 'proven', 'promising', 'fuzzy', 'noise', and 'nonsense', providing a clear framework for understanding their respective scientific validations and benefits. The discussion is not meant to replace in-depth individual research but aims to give a quick overview, helping listeners decide which areas might be worth their attention.
Special episode with Dax Shepard: F1 and the 30th anniversary of Ayrton Senna's death
In this special episode of "The Peter Attia Drive," host Peter Attia and guest Dax Shepard delve into the life, legacy, and tragic death of Formula One icon Ayrton Senna on the 30th anniversary of his passing. The discussion covers Senna's profound impact on the sport, his unique driving style, and his enduring influence on fans and drivers alike. The hosts explore not just Senna's professional achievements but also his personal attributes, such as his charisma, dedication to Brazil, and his philosophical approach to racing. The episode is both a celebration of Senna's career and a reflection on the safety advancements in motorsport that his death helped catalyze.
#299 - Optimizing muscle protein synthesis: the crucial impact of protein quality and quantity, and the key role of resistance training | Luc van Loon, Ph.D.
In a detailed conversation with Professor Luc van Loon, an expert in physiology and exercise from Maastricht University, host Peter Attia delves into the nuances of how proteins in various forms affect muscle synthesis differently. They discuss the roles of different types of proteins like whey, casein, and collagen, and how preparation methods can impact their effectiveness in building muscle. Additionally, the episode covers the significance of exercise, particularly resistance training, in enhancing muscle protein synthesis, offering a comprehensive look at both nutritional and physical approaches to muscle health.